Robotic Sample Preparation System

A significant improvement in the preparation of end-to-end NMR and LCMS samples, including the gravimetric pick and decision dispense of solids and matrix-to-matrix reformatting (including applications in GMP environments).OVERVIEWinput:
output:The solution provided by Chemspeed

Nuclear magnetic resonance (NMR) is a physical observation technique that involves the perturbation of nuclei in a strong, constant magnetic field by a weak, oscillating magnetic field (in the near field, which does not involve electromagnetic waves). The nuclei respond by generating an electromagnetic signal with a frequency that is characteristic of the magnetic field at the nucleus. input:
output:NMR is a consequence of the unique magnetic properties of specific atomic nuclei. The structure of organic molecules in solution and the study of molecular physics, crystals, and non-crystalline materials are both commonly determined using nuclear magnetic resonance spectroscopy. NMR is also frequently employed in sophisticated medical imaging techniques, including magnetic resonance imaging (MRI).input:
output:Nevertheless, the preparation of NMR samples is frequently still performed manually, which restricts highly qualified personnel to extremely time-consuming, tedious, and error-prone tasks.input:
output:Automated true one-to-one gravimetric “pick & decision dispense” of solid compounds is made possible by the SWILE technology. The simplified SWILE workflow, which includes the precision “pick & decision dispense” step, is illustrated in the scheme located at the bottom of this page. Chemspeed’s proprietary overhead gravimetric dispensing tool design, in conjunction with a second analytical on-deck balance, serves as the technology backbone.