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Rat Operant Conditioning System

Reference: 1093889Medical Research
ConfigurationBenchtop
Animal TypeFor Rats, For Mice
TypePlace Preference
ApplicationsFor Animal Research
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Product summary

A standard experimental chamber is required for the automated or manual evaluation of conditioned place preference and aversion in rodents (rats or mice). These tests are frequently employed to evaluate the reinforcing properties of drugs (or natural stimuli) and to investigate the neurobiological systems of the brain that are involved in reward and addition.input:
output:The BIOSEB Place Preference Box is a conventional experimental chamber that is designed for the automated evaluation of conditioned place preference and aversion in rodents. These tests are frequently employed to evaluate the reinforcing properties of drugs (or natural stimuli) and to investigate the neurobiological systems of the brain that are involved in reward and addition.



The Conditioned Place Preference test is designed to evaluate the potential for reward associated with a drug or other experimental condition.



The procedure entails operant conditioning, which involves the establishment of a preference for a specific environment that has been consistently associated with a subjective internal state that is induced by the tested substance or condition. The animal will spend a greater amount of time in the compartment with which it was paired when it is subsequently tested without the drug, if the drug possesses significant rewarding properties. The conditioned place preference procedure has been traditionally employed for a long time to evaluate the addictive potential of potential drugs of abuse in both the pharmaceutical industry and research. The procedure may also be altered to ascertain whether genetically modified animals are more or less susceptible to the reinforcing effects of a drug.input:
output:Principle of operationinput:
output:The experimental box is comprised of two Perspex compartments that are identical in size and are connected by a central grey corridor.

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