Isothermal Titration Calorimeter

The most reliable method for determining stoichiometry and affinity

The MicroCal PEAQ-ITC is a low volume, isothermal titration calorimeter that is highly sensitive and designed for the label-free in solution study of biomolecular interactions. It is capable of analyzing weak to high affinity binders and provides direct measurement of all binding parameters in a single experiment, utilizing as little as 10µg of sample. The system is upgradable to the fully automated MicroCal PEAQ-ITC Automated, making it ideal for laboratories that prioritize speed, sensitivity, and the capacity to handle increased workloads in the future. Additionally, semi-automated maintenance reduces operator intervention.input:
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The MicroCal PEAQ-ITC is engineered to provide exceptional sensitivity and ease of use. The system directly measures the heat that is released or absorbed during biochemical binding events, and from this data, it calculates binding affinity (KD), stoichiometry (n), enthalpy (ΔH), and entropy (ΔS). Data is generated rapidly and effortlessly with minimal sample preparation and system optimization. The analysis of weak to high affinity binders is made possible by the wide affinity range, which ensures excellent reproducibility. MicroCal ITC is an indispensable instrument for any research laboratory that investigates biomolecular interactions and requires rapid results and high sensitivity.
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output:Guided workflows that are user-friendly and include embedded help videos enable users of all levels to produce high-quality data.

A high signal-to-noise ratio increases the confidence in the quality of the data and the relevance of the thermodynamic and affinity parameters that are generated.

The production of high-quality, reproducible data is facilitated by the automated washing of the sample cell and titration syringe with detergent.