Description

Even when LC columns are advertised as being designed for basic compounds, they frequently fail to achieve sufficient resolution as a result of issues such as the leading of highly polar basic compounds, the deterioration of the peak shape of acidic compounds, or the lengthy equilibration time necessary for a low-ionic-strength acidic mobile phase. Shim-pack Arata, which was specifically engineered to provide an unparalleled peak shape for basic compounds, has resolved all of these concerns.input:
output:Characteristicsinput:
output:A Wide Range of Compounds are Elegantly Designed with an Unmatched Peak Shapeinput:
output:
The peak shape of basic compounds could be unmatched, while the peak shape of acidic compounds could be maintained.

Even in the presence of weak ion pairing acids, peptides exhibit exceptional separation performance.input:
output:TFA-containing mobile phases are frequently employed to achieve a good peak shape of peptides during reversed phase chromatography, as the ion pairing effect is relatively robust. Nevertheless, TFA may result in ion suppression during LC/MS (/MS) analysis. The Shim-pack Arata LC column was capable of achieving exceptional peak shape and separation performance for peptides, even when the mobile phase contained 0.1 % formic acid (weak ion paring acid).input:
output:Rapid Equilibration is Possible Despite the Presence of Acidic Mobile Phases with Low Ionic Strengthinput:
output:Common issues include long equilibration times and a peak shape when analyzing basic compounds on a typical ODS column with a low ionic strength acidic mobile phase. Shim-pack Arata LC columns can be rapidly equilibrated in acidic mobile phases with low ionic strength, resulting in stable retention times and an excellent peak shape.

 

 

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MAECENAS IACULIS

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ADIPISCING CONVALLIS BULUM

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