Fluidized Bed Granulator

Pharmaceutical companies have implemented fluidized bed systems for decades. The mixture of dry powder particles is compressed by the addition of an aqueous or alcoholic granulation medium. A volatile solvent is present in the fluid and can be eliminated through the process of drying. For an extended period, top-spray was the predominant method for fluidized bed solutions. Nevertheless, the advantages of systems with tangential spray nozzles have become increasingly apparent, and as a result, they are increasingly replacing top-spray granulators. L.B. Bohle’s fluid bed granulation portfolio encompasses production-scale systems and research and development systems for small production volumes.

In order to optimize fluidized beds, L.B. Bohle implements the Bohle Uni Cone BUC® process.

A conical displacement cone is affixed to a specially slotted air distributor plate, the patented Bohle Uni Cone BUC®. This design enables the particles to be fully fluidized. This uniform film, which is achieved without any twins, is achieved on pellets, for example, through tangential particle motion.input:
output:A high-volume expansion is not necessary for the fluidized particles or granules, as they move tangentially at a relatively low fluidization height. This results in a decrease in the necessary installation height, which in turn saves production floor space and costs.input:
output:The uninterrupted air flow through the product bed is guaranteed by at least six filter elements of the BFS that can be cleaned separately.Drying, granulation, and coating can be performed without the need for modification.input:
output:Granulation, coating, and drying can be executed in a single system without the necessity of reconfiguring the equipment, which is another benefit of the tangential design in L.B. Bohle facilities.