Endobronchial Valve Bioprosthesis

Zephyr® Endobronchial Valve

The Zephyr® Endobronchial Valve is an endoscopic lung volume reduction therapy that has been demonstrated to significantly enhance lung function, exercise capacity, and quality of life for emphysema patients in four randomized, controlled clinical trials and in 12,000 patients worldwide.input:
output:It provides a prospectively proven method for predicting responders in conjunction with its diagnostic companion products. It is also intended to be removable, thereby preserving patients' future treatment options.input:
output:The National Institute for Health and Care Excellence (NICE) of the United Kingdom has revised its guidance for endobronchial valves, concluding that the current body of evidence is sufficient to warrant their routine use. The NICE guidance has been modified in light of the safety and efficacy data from numerous randomized clinical trials that have assessed the Zephyr EBV. This treatment has been shown to provide clinical and quality of life benefits, as well as long-term safety for eligible patients.input:
output:A flexible delivery catheter is employed to deliver Zephyr valves to the designated airways using a standard bronchoscope.

The one-way valve, once it is implanted, prevents airflow into the diseased region while allowing trapped air and fluids to escape.The diseased region's volume may be reduced, thereby enabling healthier regions to expand and operate more efficiently.