Automatic Laboratory Extractor

Solid-phase extraction is designed to selectively isolate target analytes from a complex sample or a large sample volume in preparation for chromatographic analysis (e.g. HPLC, GC, TLC). Merck’s LiChrolut® columns employ robust yet reversible interactions between the analyte and the stationary surface, as solid-phase extraction operates on the basis of liquid chromatography. Hydrophobic (Van-der-Waals forces), polar (hydrogen bonding, dipole-dipole forces), and ion exchange interactions are among the most common interactions.input:
output:It is crucial to conduct appropriate sample pretreatment in order to prevent interactions between the stationary phase and matrix. This enables the enhancement of the contrast between the analyte and matrix components’ chemical properties by adjusting the pH or ionic strength of the sample solution. The analyte is enriched as a narrow zone on the stationary phase under these conditions. Selective elution of the analytes may occur after a washing step, which is designed to eliminate potential adsorbed sample components.