Animal Research Organ Perfusion System

The isolated perfused liver and isolated perfused kidney models are dependable standards for pharmacological research. The rat has been the donor animal in the majority of these studies; however, there has been a recent surge in interest in the mouse model. The Radnoti Liver/Kidney system is capable of being utilized in experimental protocols that are either re-circulating or non-re-circulating, utilizing constant pressure or constant flow.Radnoti in-vitro liver/kidney chamber:The donor's liver is extracted.
suitable for both mice and rats
water-jacketed and circular, with a glass lid assembly.flat-bottomed with a side-mounted drain.

Each of the three ports allows for the introduction of two cannulas for organ perfusion and one for the removal of bile samples.

The liver or kidney is mounted using luer-hubbed, paired stainless steel cannula that are connected to flexible inlet and outlet lines.

The chamber's lid is equipped with a central threaded mount that facilitates the attachment of a fiber optic cable. This cable is employed for optical measurements of endogenous nucleotides or a variety of fluorescent indicators.