Animal Research Organ Perfusion System

Isolated rat kidney or liver measurement systeminput:
output:For decades, the isolated perfused liver and isolated perfused kidney models have been a standard technique for pharmacological research. The MDE Ltd. whole organ perfusion system is a dependable and compact piece of equipment that is designed to modify the standard basic methods that are commonly employed in rodents.

The MDE isolated liver or kidney perfusion system offers researchers a precise and adaptable instrument for the investigation of pharmacological processes and organ function. This system enables the precise manipulation of perfusate composition, which in turn facilitates investigations into drug metabolism, organ function, and responses to a variety of interventions.

The primary benefit of the MDE isolated liver and kidney perfusion setups is their innovative design and functionality, which offer a variety of significant advantages:

Preservation of Organ Function: The system ensures optimal functionality by maintaining isolated organ function within a horizontally placed evaporation chamber, thereby preventing deformation of the organ’s vasculature.

Temperature and Perfusion Control: The optimal conditions for organ viability and functionality are maintained by the precise temperature control of both the evaporation chamber and perfusion buffer, as well as the perfusion pump-controlled flow of buffers.

Sample Collection for Analysis: The collection of bile, urine, and organ-passed buffer fractions is facilitated by the relatively low perfusion buffer volume, which enables the qualitative or quantitative analysis of substances such as drugs, drug metabolites, and hepatic enzymes.